UPSC CSAT : Reading comprehension Home Exercise- 05, PASSAGE A

Saturday 7 March 2015

Reading comprehension Home Exercise- 05, PASSAGE A

4.       According to Snyder et al, all of the following compounds can bind to specific receptors in the brain EXCEPT

            A.      IBMX  
            B.      Caffeine
            C.      Adenosine
            D.      Phosphodiesterase

5.       Snyder et al suggest that caffeine’s ability to bind to A₁ and A ₂ receptors can be at least partially attributed to which of the following?
             A.      The chemical relationship between caffeine and phosphodiesterase
             B.      The structural relationship between caffeine and adenosine
            C.      The structural similarity between caffeine and neurotransmitters
             D.      The ability of caffeine to stimulate behavior

6.       The author quotes Snyder et al, most probably in order to
           A.      Reveal some of the assumptions underlying their theory
           B.      Summarize a major finding of their  experiments
          C.      Point out that their experiments were limited to the mice
           D.      Indicate that their experiments resulted only in general correlations

Answer and Explanations
4.       D    the first paragraph explains that both adenosine and caffeine bind to receptors in the brain. The fourth paragraph attests to the ability of theophyline to bind to the receptors. The last paragraph describes IBMX as a compound that binds to adenosine receptors. Thus the exception has to be the enzyme phosphodiesterase.
5.       B     The A₁ and A₂ receptors, so look at the surrounding material. Snyder et al propose that caffeine, which is structurally similar to adenosine binds to both types of receptors, just as adenosine does, caffeine’ ability to bind to these receptors may be due to this structural similarity to adenosine .
6.       B     The third paragraph starts with evidence supporting the new hypothesis on the basis of experiments with mice. The quotation then begins in general, a phrase that implies a summary of the results of the work with mice. The quoted material explains that the more the compounds were able to bind to the receptors the greater the stimulatory effect. This major finding supports the hypothesis.


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